Bacteria from Gum Disease May Play a Role in Development of Esophageal Cancer

Posted on February 29, 2016 by Disability Help Group

Researchers have long connected the development of esophageal cancer to conditions that damage the DNA in the lining of the esophagus. Researchers also sometimes consider alcohol and tobacco use, acid reflux, and other health conditions that damage the esophagus risk factors for esophageal cancer.

Recently, a team of doctors from the University of Louisville and Henan University of Science and Technology collaborated on research of another potential esophagus-damaging element: bacteria.

The research, published in BMC Genomics, looked at 100 patients with esophageal squamous cell carcinoma (ESCC), one of the two common types of esophageal cancer. The researchers examined and sampled the tissue of the esophagus lining to produce cancerous samples and non-cancerous samples adjacent to the cancer. Researchers also took samples of esophagus lining from a group of 30 non-cancerous patients for a control group.

The P. gingivalis bacteria, known for causing periodontitis or gum disease, was present in 61 percent of the cancerous tissue samples and 12 percent of the non-cancerous tissue samples. The control samples had no P. gingivalis bacteria present.

The scientists must conduct further research in order to determine if the ESCC cells are just a good growing medium for this bacteria or if the bacteria actually encourages the development of the cancer. Meanwhile, doctors are now looking at the potential for using antibiotics to treat esophageal cancer caused by P. gingivalis.

When Esophageal Cancer Diminishes Quality of Life You May Qualify for Disability Benefits

Esophageal cancer can cause difficulty swallowing and talking and may result in the need for assistive equipment to continue eating, drinking, and communicating. If cancer of any type has disabled you or a loved one, the Disability Help Group is here to help you file a claim for benefits.

Contact us online or call us at 1-(800)-800-3332 to schedule a consultation with our disability advocates!