Blocking Cells from Entering Bloodstream May Stop Breast Cancer Spread
Like many cancers, breast cancer mortality rates increase when it spreads to other parts of the body. Breast cancer cells often travel through the bloodstream, allowing them to cause cancer in other organs such as the liver, lungs, and ovaries.
In order to potentially prevent cancer cells from entering the bloodstream, researchers at the Institute of Cancer Research in London and the University of Manchester are looking at the mechanisms that allow cancer cells into blood vessels. The study, published in Science Signaling, looked at the EPHA2 protein that sits on the surface of the cells that line the blood vessel walls.
EPHA2 is a signal receptor that communicates with any cell trying to enter the blood vessel’s walls. Cancer cells communicate with this protein and switch the receptor off, allowing the cancer cells to push past the barrier and spread to the rest of the body.
Researchers are now looking for a method of keeping this protein switched on to keep the cancer cells trapped within the blood vessel walls and preventing them from moving into the bloodstream. This could help reduce the spread of breast cancer and help improve localized treatment.
Breast Cancer is One of the Most Easily Spread Cancers
When a patient goes into remission from breast cancer, she is still at a higher risk for developing many other types of cancer. Once diagnosed, a cancer patient must continuously undergo follow-up checks to ensure the cancer has not returned or metastasized elsewhere.
If you or a loved one can no longer work due to disabling conditions caused by cancer you may qualify for Social Security disability benefits. Contact the Disability Help Group online or call us at 1-(800)-800-3332 to schedule a consultation with our disability advocates!