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Gene May Be Linked to Recurrence and Shortened Survival Rate in Colorectal Cancer Patients

Posted on October 16, 2015 by Disability Help Group

Colorectal or bowel cancer is one of the most prevalent types of cancer in the United States with a 1 in 20 lifetime risk. There have been some great strides in early detection and treatment, but the disease remains a highly disabling condition with a high mortality rate. New research published in the journal Gut found a specific gene, snoRA42, may predict a higher risk of recurrence of colorectal cancer and a shorter expected survival time. Analysis of four different snoRNAs from 274 tissue samples found that all four were more prevalent in cancerous compared to normal cells. They found that higher levels of snoRA42 were associated with higher risk of recurrence in another area of the body. They also found that higher levels of snoRA42 in laboratory-grown cells caused uncontrolled cellular division, spreading of cancer cells, as well as resistance to the programmed cellular death. The identification of high snoRA42 prevalence in a patient’s biomarkers could help doctors make more informed choices about treatment and prognosis. This is an especially useful find for cases where a doctor is questioning the effectiveness of chemotherapy for a patient. Bowel cancer has a high recurrence rate, which often leads to rapid disease progression and eventual death. It is often in the recurrence stage that patients become unable to work and may qualify for disability benefits.

Disability Help Group Can Assist Patients Trying to Qualify for Benefits

Proving qualification for Social Security disability benefits can be difficult to accomplish. The strict requirements and complicated application and appeals processes leave many claimants frustrated and ready to give up. If you need help, contact Disability Help Group. Contact us online or call us at 1-(800)-800-3332 to speak with our disability advocates!